Drugs for Acne

Courtesy of Muhammad Naseem Abbas via LinkedIn

Pathophysiology of Acne Treatments

The pathophysiology of acne and the different drugs used for its treatment.

1. Sebaceous Gland: This is where acne begins, with sebum production being influenced by androgens.

2. Normal Follicle: In a healthy follicle, sebum and keratinocytes are able to flow out freely.

3. Follicle Plugged by Sebum and Keratinocytes: When the follicle becomes plugged, a microcomedone forms as the initial acne lesion.

4. Inflammatory Acne: If the microcomedone becomes inflamed, it can progress to inflammatory acne.

5. Comedones: These are the primary lesions of acne, including both open (blackheads) and closed (whiteheads) comedones.

6. C. acnes: This bacterium is involved in the development of acne, contributing to inflammation.

7. Drugs for Acne: The diagram lists various drugs used to treat acne, including adapalene, azelaic acid, benzoyl peroxide, isotretinoin, nicotinamide, cyproterone, clindamycin, tetracyclines, and trimethoprim. These drugs work in different ways to target the underlying causes of acne, such as reducing sebum production, inhibiting bacterial growth, and promoting skin cell turnover.

This diagram provides a comprehensive overview of the pathophysiology of acne and the pharmacological options available for its treatment.

Source: Muhammad Naseem Abbas via LinkedIn

MM Health

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